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In addition, at various concentrations, triptolide was found to induce the phosphorylation of p53 within the serine-15 residue in HepG2 cells. Activating the tumor suppressor gene p53 can induce the apoptosis of liver most cancers cells 36.31. As well as its anticancer effect on NSCLC, triptolide also can focus on the Nrf2 pathway to lessen the che